Gilson Connect
Gilson's GX-Series Liquid Handlers, paired with TRILUTION® LH software and GEARS, can integrate with QINSTRUMENTS thermal and shaking modules. This powerful combination enables automated workflows involving heating, cooling, and agitation—ideal for redissolving compounds, kinetic testing, derivatization before SPE, and liquid-liquid extractions. Expand your system’s capabilities with precision temperature control and flexible labware support—all fully automated for increased efficiency and reliability.
Peak-based fraction collection has the advantage that it’s based on real-time information. Your detector reveals a peak of interest, and the peak meets the criteria for collection. However, your molecules of interest are in the detector when you see the signal, and they need to pass through more tubing and parts before they can be collected. So how do you know when it is best to collect your sample? By knowing the fraction delay time.
Chromatography plays a crucial role in the chemical and pharmaceutical industries. New drug innovation, pilot studies, and process development are a few examples of how it's used. Preparative chromatography is a method used to separate and purify target compounds derived from complex mixtures so that they can be used in other applications. When conducting these separations, there are certain dependencies that must be considered as scientists develop their methods. In this video, you'll learn more about these interdependent relationships involved in chromatographic separations.
Fraction collection can be conducted in a variety of manners. Most commonly, however, fractions are collected either based on a simple function of time or more complex parameters set off by the signals from your detectors. Learn more in our helpful video, which highlights 8 common questions about fraction collection.
Preparative high performance chromatography (prep HPLC or LC) plays a crucial role in many industries. It is used to isolate and purify desired compounds, removing impurities and contaminants that can affect the quality and performance of the end product. In this video, we answer your questions about prep HPLC and how it can fit into your lab's purification workflows.
There are many different chromatography techniques, but which is right for your experiment? This video will give an overview of the main differences between analytical and preparative chromatography and help guide you to the technique that is best for your lab's purification research.
Sample preparation for any form of analysis can be tedious and time-consuming, and efforts to automate this process have been long and fruitful. Today, many different types of liquid handlers exist that can perform a variety of functions to increase throughput tremendously. In this application note, we demonstrate one example of sample prep by taking a common but complicated screening method for optimizing liquid-liquid chromatography run parameters and automating the process. We also showcase the use of liquid level detection in the precise liquid handling of biphasic solutions
In high performance liquid chromatography (HPLC), the selection of an appropriate mode of detection is vital to the success of any separation. To this end, there are numerous choices one might consider when configuring a new HPLC setup. Mass spectrometry (MS) is an alternative method of detection and identification that is much more robust than UV. Here, we describe how the VERITY 1920 Mass Spectrometer allows for MS detection capabilities at an affordable price for HPLC fraction collection.
Fractionation, or the separation of a mixture of molecules into different parts or “fractions,” helps scientists understand and/or use a complex solution. Collecting and isolating individual fractions from a mixture can enable many downstream applications as specific molecules can be separated based on physical and chemical properties. In this article, we explore the basics of fraction collection, including applications, parameters, and available solutions for your lab.
When choosing a high performance liquid chromatography (HPLC) system, it's important to consider how your future needs may evolve from your current needs. In this article, you’ll learn about the advantages of modular HPLC systems when it comes to current experimental needs and how the ability to swap out HPLC components safeguards the future of your system and your research.
