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Technical Notes
The manual cyclization step in a peptide purification workflow is time-consuming and can easily become the rate-limiting step of the whole workflow, leading to delays in peptide production. Automating a drop-wise cyclization process using a liquid handler with a large rack capacity and incorporating automatic orbital shaking is an ideal solution to this workflow bottleneck. Learn more in this technical note.
In high performance liquid chromatography (HPLC), the selection of an appropriate mode of detection is vital to the success of any separation. To this end, there are numerous choices one might consider when configuring a new HPLC setup. Mass spectrometry (MS) is an alternative method of detection and identification that is much more robust than UV. Here, we describe how the VERITY 1920 Mass Spectrometer allows for MS detection capabilities at an affordable price for HPLC fraction collection.
Get fast, high-yield, and high-purity isolations without the need for long washing steps. This is possible thanks to our exclusive Exclusion-based Sample Preparation (ESP™) technology. It is perfect for capturing weakly bound protein complexes without subjecting them to high shear forces from pipette-based wash steps. Plus, it prevents contamination, dilution, or discarding of the original samples.
ICP-MS analysis is a technique of choice in many laboratories to quantify trace elements in many matrices. Automating this process reduces manual handling errors and provides traceability where manual preparation has none. This technical note shows how the use of a Gilson liquid handler and TRILUTION® LH Software makes it possible to automate those acidic dilutions prior to analysis by ICP-MS.
This guide provides information about fraction collection techniques using TRILUTION® LC Software.
When performing high performance liquid chromatography (HPLC), efficiency is key to get the most throughput out of your instruments. Instead of purchasing additional instrumental setups, there are several ways to increase the efficiency of a single instrument. Switching valves, like the Gilson VALVEMATE® II Valve Actuator, can allow for the connection of multiple columns for column switching to expand what is possible on a single system alone.
Gilson's GX-Series Liquid Handlers, paired with TRILUTION® LH software and GEARS, can integrate with QINSTRUMENTS thermal and shaking modules. This powerful combination enables automated workflows involving heating, cooling, and agitation—ideal for redissolving compounds, kinetic testing, derivatization before SPE, and liquid-liquid extractions. Expand your system’s capabilities with precision temperature control and flexible labware support—all fully automated for increased efficiency and reliability.